Cenforce-25 Tablets Cenforce-25 contains Sildenafil Citrate, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). During sexual stimulation, nitric oxide (NO) is released in the corpus cavernosum, activating guanylate cyclase and increasing intracellular levels of cGMP. Sildenafil inhibits PDE5, preventing the enzymatic degradation of cGMP in the vascular smooth muscle of the penis and promoting cGMP accumulation. Increased cGMP levels induce smooth muscle relaxation and arterial vasodilation within the erectile tissue, enhancing blood flow to the corpus cavernosum and enabling a natural erectile response. Cenforce-25 is indicated for the treatment of erectile dysfunction (ED) in adult males, serving as a low-dose starting option or for patients sensitive to higher dosages.