Mebenda Plus Tablets MEBENDA PLUS® combines two potent antiparasitic agents, Mebendazole and Ivermectin, offering dual-action broad-spectrum coverage against gastrointestinal and systemic parasitic infestations. Mebendazole selectively binds to cytoplasmic tubulin in helminths, inhibiting microtubule assembly, blocking glucose uptake, and causing glycogen depletion and metabolic starvation. Ivermectin selectively binds with high affinity to glutamate-gated chloride ion channels in invertebrate nerve and muscle cells, increasing cell membrane permeability to chloride ions and causing hyperpolarization, flaccid paralysis, and parasite death. This synergistic combination is indicated for comprehensive control and eradication of complex, mixed, or resistant worm infestations, including roundworms, hookworms, whipworms, pinworms, and threadworms.