Trombonat 25 Trombonat 25 contains Eltrombopag Olamine, an orally active thrombopoietin receptor agonist. It works by interacting directly with the transmembrane domain of the human TPO receptor on megakaryocytes, signaling bone marrow precursor cells to proliferate and differentiate into functional platelets. This targeted action boosts overall blood platelet counts, helping reduce the risk of bleeding episodes in individuals affected by chronic immune thrombocytopenia (ITP), severe aplastic anemia, or thrombocytopenia associated with Hepatitis C infection.