EFAVIR 200 Capsules EFAVIR 200 contains Efavirenz, a non-nucleoside reverse transcriptase inhibitor (NNRTI) targeting Human Immunodeficiency Virus Type 1 (HIV-1). It acts via direct, non-competitive binding to HIV-1 reverse transcriptase, inducing an allosteric conformational shift that inhibits viral RNA-dependent and DNA-dependent DNA polymerase activity. This prevents the synthesis of viral complementary DNA (cDNA) and halts replication. It is indicated as part of combination antiretroviral therapy (cART) for the treatment of HIV-1 infection in adults and pediatric patients.