Enzamide 40 Capsules Enzamide-40 contains Enzalutamide, a nonsteroidal androgen receptor inhibitor that acts at multiple steps in the androgen receptor signaling pathway. It competitively inhibits the binding of androgens to androgen receptors, prevents nuclear translocation of activated receptors, and inhibits the binding of the activated androgen receptor to DNA. It is indicated for the treatment of adult men with metastatic and non-metastatic castration-resistant prostate cancer (CRPC) and metastatic castration-sensitive prostate cancer (mCSPC).