EVERMIL 5 Tablets EVERMIL 5 contains Everolimus, an inhibitor of mammalian target of rapamycin (mTOR), a serine-threonine kinase downstream of the PI3K/AKT pathway. By binding to the intracellular protein FKBP-12, it forms a complex that blocks mTOR complex 1 (mTORC1), thereby inhibiting cell growth, proliferation, protein synthesis, and angiogenesis. It is indicated for the treatment of advanced hormone receptor-positive, HER2-negative breast cancer, advanced renal cell carcinoma (RCC), neuroendocrine tumors (NET) of pancreatic, gastrointestinal, or lung origin, and renal angiomyolipoma associated with tuberous sclerosis complex (TSC).